This prompt gets personal. Drawing from your own life experiences, take the most difficult decision you ever had to make and then write a fictional story based on that choice. Obviously, this lends itself to serious pieces of fiction, but it could be turned into comedy with a poignant message.
Based on a tough experience in my life I generated this pitch.
Separated - John and his son have been a team since the day that Johnny was born. Life blind-sides him when his ex-wife appears one day with a court order giving her temporary custody of Johnny. The one constant in John’s life has been his son’s love and without it he wonders how he can survive the daily grind. Knowing that if he creates a scene it will only cause more trouble for Johnny, he says goodbye. In the days to come he will not only have to find a way to return Johnny home, but also adapt to life without him.